methylene blue, gentian violet, and ovine forestomach wound dressings to HS lesions

Hydrofera Blue is an antibacterial foam dressing that contains methylene blue and gentian violet to manage wounds. This is a safe, non-cytotoxic product that can be worn for 7 days while not inhibiting growth factors. This products wicks bacteria into the foam and away from the wound surface using natural negative pressure through capillary flow.

Endoform (ovine forestomach) is a natural dermal template used in all phases of wound healing. This product helps to stabilize, build, and organize tissue in acute and chronic wounds.

Hypafix tape aids in stabilization of wound dressings. This productIt is easy to apply, skin friendly, and comfortable to use.

methylene blue, gentian violet, and ovine forestomach wound dressings

Patients will not receive any drugs, but will participate to experiments involving electroencephalograpy, pupillometry and light administration.

Recording of the electrical activity of the brain, of the heart. Pupil size will be analyzed. The effect of blue light administration will be assessed on those parameters.

electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration

Subjects will not receive any drugs, but will participate to experiments involving electroencephalograpy, pupillometry and light administration.

Transcutaneous vagus nerve stimulation will be performed in helathy subjects, as well as the recording of the electrical activity of the brain, and of the heart. Pupil size will be analyzed. The effect of blue light administration will be assessed on those parameters.

transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Inci Cakiroglu, Phd student

Evoked potentials will be recorded from brain area M1 (motor cortex) in combination with a speech motor learning procedure known as adaptation to altered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

Adaptation

motor evoked potentials will be obtained in each recording block

Motor evoked potentials

Evoked potentials will be recorded from brain area A1 (auditory cortex) in combination with a speech motor learning procedure known as adaptation to altered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

auditory evoked potentials will be obtained in each recording block

Auditory evoked potentials

Evoked potentials will be recorded from brain area S1 (somatosensory cortex) in combination with a speech motor learning procedure known as adaptation to altered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

Somatosensry evoked potentials will be obtained in each recording block

Somatosensory evoked potentials

Evoked potentials will be recorded from brain area M1 (motor cortex) in combination with unaltered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

Adaptation baseline

Evoked potentials will be recorded from brain area A1 (auditory cortex) in combination with unaltered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

Evoked potentials will be recorded from brain area S1 (somatosensory cortex) in combination with unaltered auditory feedback. Retention of learning will be tested 24h later along with additional evoked potential recordings.

Participants undergoing ventricular tachycardia ablation per standard of care will also have cellular action potential of the ventricular myocardium assessed with the MAP catheter.

The EasyMap catheter is a temporary quadripolar catheter for recording monophasic action potentials and for intracardiac pacing. During a standard of care VT ablation, the MAP catheter will be used to study cellular action potential of the ventricular myocardium, which cannot be done on traditional catheters. The catheter is placed on the myocardium (similar to other traditional catheters) and a recording signal is transmitted to the workstation. Using the MAP catheter the will not interrupt or distort any of the standard treatment procedures.

임상시험 현황

메틸렌 블루, 젠티안 바이올렛, 양전위 상처 드레싱

뇌파검사, 심전도, 동공측정법, 유발전위, 빛 투여, 경피적 미주신경 자극, 뇌파검사, 동공측정법, 심전도, 빛 투여

적응, 적응 기준선, 운동 유발 전위, 청각 유발 전위, 체성감각 유발 전위

단상 활동 전위(MAP) 카테터