Patients will receive active treatment with the device every other day over 8 weeks.

Patients receive treatment every other day via a headband that delivers electrical stimulation to the retina

Repetitive, Transorbital Alternating Current Stimulation (rtACS)

Study Team

Patients undergo two fractions of low dose orbital EBRT on 2 consecutive days. Patients experiencing stable or progressive disease after 12-16 weeks of EBRT undergo additional low dose orbital EBRT over 10 fractions. Patients experiencing partial response or minimal response 1 year after EBRT also undergo low dose orbital EBRT over 10 fractions.

External Beam Radiation Therapy

Participants receive radiation to entire involved orbit for a total dose of 4 Gy in 2 fractions over two consecutive days with external beam radiotherapy. If there is stable disease or progressive disease, an additional 20 Gy administered to involved site. If there are two consecutive evaluations with no change in disease burden then an additional 20 Gy administered. At one year if there is persistent disease, an additional 20 Gy administered to involved site.

반복적, 안와교류자극(rtACS)

외부 방사선 치료, 안와 방사선 치료

안와하 차단, 국소 비강 부피바카인